The Osteopathic Research Center focuses on the clinical efficacy and mechanisms of action of osteopathic manipulative treatment (OMT). In 2011, the ORC completed the 455-person, NIH-funded study, the OSTEOPAThic Health outcomes In Chronic low back pain Trial (OSTEOPATHIC Trial).The ORC is currently enrolling subjects for a study on chronic low back pain in patients with Type 2 diabetes mellitus.

In addition to its clinical studies, ORC faculty are conducting mechanistic research to assess the response to OMT technique at the molecular and cellular level.

Faculty at the ORC have been recognized for their research accomplishments through national awards, invitations to present at national and international conferences, and by serving in consultative roles with such organizations as the World Health Organization.