The Osteopathic Research Center, founded in 2002, focuses on the clinical efficacy and mechanisms of action of osteopathic manipulative treatment (OMT).

In 2011, the ORC completed the 455-subject, NIH-funded OSTEOPAThic Health outcomes In Chronic low back pain Trial (OSTEOPATHIC Trial) through its clinical research unit. To our knowledge, the OSTEOPATHIC Trial is the largest clinical trial to date involving OMT. The ORC's health services and policy research is providing the evidence to develop clinical practice guidelines for OMT in conditions such as low back pain.

In addition to the clinical studies it conducts, cutting-edge basic science research is assessing the response to OMT techniques, such as lymphatic pump, at the molecular and cellular level.

Faculty at the ORC have been recognized for their research accomplishments through national awards, invitations to present at national and international conferences, and by serving in consultative roles with such organizations as the World Health Organization.