Hepatitis B Hepatitis B is a viral disease that may be transmitted through activities which result in exchange of blood or blood-derived fluids, and through sexual activity between an infected and a susceptible person. The risk to international travelers depends on the prevalence of hepatitis B in the areas being visited, the extent of potential contact with infected persons, and the duration of travel. Hepatitis B vaccination is recommended for high risk travelers. Current hepatitis B vaccines in the United States are produced through recombinant DNA technology, and no longer use human plasma. In the past, several months have been needed to administer the three doses of hepatitis B vaccine necessary for optimal protection; however, new research suggests that the vaccine series may be effectively given over a three-week period in many travelers, provided that a fourth booster dose is received one year later. Studies suggest that hepatitis B vaccine provides long-term protection, generally lasting for more than 10 years. A combined hepatitis A and hepatitis B vaccine in now available. If you wish to receive hepatitis B vaccine, please call us for a clinic appointment.