Advanced Mass Spectrometry and Proteomics Laboratory
Publications:
Expression Profiling and Proteome Characterization
Posttranslational Modifications
- Identification of carbonylation sites in apomyoglobin after exposure to 4-hydroxy-2-nonenal by solid-phase enrichment and liquid chromatography-electrospray ionization tandem mass spectrometry. J Mass Spectrom.2010 April;45(4):398-410. Rauniyar N, Prokai-Tatrai K, Prokai L.
- Detection and identification of 4-hydroxy-2-nonenal Schiff-base adducts along with products of Michael addition using data-dependent neutral loss-driven MS3 acquisition: method evaluation through an in vitro study on cytochrome c oxidase modifications. Proteomics.2009 Nov;9(22):5188-93. Rauniyar N, Prokai L.
- Characterization of 4-hydroxy-2-nonenal-modified peptides by liquid chromatography-tandem mass spectrometry using data-dependent acquisition: neutral loss-driven MS3  versus neutral loss-driven electron capture dissociation. Anal Chem.2009 Jan;81(2):782-9. Rauniyar N, Stevens SM, Prokai-Tatrai K, Prokai L.
- Factors that contribute to the misidentification of tyrosine nitration by shotgun proteomics. Mol Cell Proteomics.2008 Dec;7(12):2442-51. Stevens SM, Prokai-Tatrai K, Prokai L.
- Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria. J Mass Spectrom.2007 Dec;42(12):1583-9. Prokai L, Yan LJ, Vera-Serrano JL, Stevens SM, Forster MJ.
- Fourier transform ion cyclotron resonance mass spectrometry of covalent adducts of proteins and 4-hydroxy-2-nonenal, a reactive end-product of lipid peroxidation. Anal Bioanal Chem.2007 Nov;389(5):1421-8. Rauniyar N, Stevens SM Jr, Prokai L.
- Rapid characterization of covalent modifications to rat brain mitochondrial proteins after ex vivo exposure to 4-hydroxy-2-nonenal by liquid chromatography-tandem mass spectrometry using data-dependent and neutral loss-driven MS3 acquisition. J Mass Spectrom.2007 Dec;42(12):1599-605. Stevens SM Jr, Rauniyar N, Prokai L.
De Novo Protein Sequencing
- De novo sequencing of a 21-kDa cytochrome c4 from Thiocapsa roseopersicina by nanoelectrospray ionization ion-trap and Fourier-transform ion-cyclotron resonance mass spectrometry. J Mass Spectrom.2007 Dec;42(12):1569-82. Branca RM, Bodó G, Bagyinka C, Prokai L.
LC/MS: Pharmacokinetics & Drug Distribution
- Centrally acting and metabolically stable thyrotropin-releasing hormone analogues by replacement of histidine with substituted pyridinium. J Med Chem.2004 Nov 18;47(24):6025-33. Prokai L, Prokai-Tatrai K, Zharikova AD, Nguyen V, Perjesi P, Stevens SM Jr.
- Integration of mass spectrometry into early-phase discovery and development of central nervous system agents. J Mass Spectrom.2001 Nov;36(11):1211-9. Prokai L, Zharikova AD, Janáky T, Li X, Braddy AC, Perjesi P, Matveeva L, Powell DH, Prokai-Tatrai K.
- Exploratory pharmacokinetics and brain distribution study of a neuropeptide FF antagonist by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry. Rapid Commun Mass Spectrom.2000;14(24):2412-8. Prokai L, Zharikova AD, Janáky T, Prokai-Tatrai K.